Ritonavir Form III
Ritonavir Form III: Lightning strikes twice at the same time, 137 miles apart Abstract Polymorph screening is a crucial step in the characterization and development of pharmaceuticals. The 1998 recall of ritonavir upon the unexpected appearance of the more stable Form II polymorph remains a notorious case of disappearing polymorphs as the presence of Form […]
Maleate salts of bedaquiline
Summary Bedaquiline is one of two important new drugs for the treatment of drug-resistant tuberculosis (TB). It is marketed in the US as its fumarate salt, but only a few salts of bedaquiline have been structurally described so far. We present here five crystal structures of bedaquilinium maleate. Dale K. Purcell, Ph.D. of Chemical Microscopy […]
Crystal structures of salts of bedaquiline
Bedaquiline is one of two important new drugs for the treatment of drug-resistant tuberculosis (TB). This paper discusses the crystalline structure of three salts of bedaquiline. Dale K. Purcell, Ph.D. of Chemical Microscopy LLC performed the spectroscopic analyses as reported.