Resonant Acoustic Mixing: Enhancing Low-Dose Blend Uniformity
Our paper investigates sample preparation techniques to improve the uniformity of low-dose pharmaceutical blends mixed using resonant acoustic mixing (RAM) technology. The study focuses on a challenging active pharmaceutical ingredient, caffeine, and its blending with lactose monohydrate, for which achieving acceptable homogeneity has been difficult. Researchers explored practical strategies like pre-processing with RAM, sieving, and […]